The interfacial tension (IFT) and wettability are the two major influencing factors for enhanced oil recovery. The decrease in IFT and altering the wettability of the rock towards water wet helps to increase the crude oil production from the depleted reservoir. The detailed literature review shows that the low salinity water (LSW) containing surfactant and nanoparticles helps to achieve ultra-low IFT of oil-water systems. Further, the metallic ions and the nanoparticles present in the low salinity water helps to alter the wetting condition of the reservoir rocks. In the present study, we have prepared a nanofluid (NF) of silica nanoparticles dispersed in low salinity water containing anionic surfactant (SDBS). The addition of an anionic surfactant helps to improve the stability of the silica nanoparticle in the aqueous solution. The stability study of the silica NF (500 ppm to 3000 ppm) is characterized using zeta potential measurement and visual test. The IFT of pure hydrocarbons (n-heptane, n-decane, benzene and toluene), model oil A, model oil B, and crude oil-NF system by varying concentrations of silica nanoparticles from 500 to 3000 ppm have been studied. The IFT decreases for aliphatic hydrocarbon (n-heptane, n decane)/ Model oil A-NF system. Conversely, IFT increases for aromatic hydrocarbon (benzene, toluene), model oil B/crude oil-NF system. The wettability alteration of quartz plate alters from intermediate-wet to water-wet with increasing the concentration of the silica nanoparticles in NF. Adsorption of surfactant on the rock representative surface in presence of silica nanoparticle have been studied with the help of adsorption isotherms. The adsorption of surfactant on rock representative surface reduced form 2.5 mg/g to 1.5 mg/g with increasing the concentration of silica nanoparticles from 0 ppm to 3000 ppm