Human hand plays a unique role in accomplishing daily life activities. Among various activities, grasping is one of the everyday activities performed by healthy individuals. Object stabilization while grasping is a vital aspect to consider for safe handling. In general, during the five-finger grasping of an object that experiences external torque changes, our central nervous system prefers to employ the strategy of mechanical advantage principle. The reason is to minimize the total effort while restoring the equilibrium of the grasped object. According to the mechanical advantage hypothesis, peripheral fingers (index and little) with longer moment arms for normal forces produce greater normal force during torque production tasks than the central fingers (middle and ring) with shorter moment arms. The current research involved investigating this hypothesis when the contribution of the thumb to support the load of the grasped object was artificially reduced. The experimental handle consisted of a vertical railing fitted on the thumb side of the handle frame with a slider platform mounted on the railing, and a thumb force sensor placed on the platform. Fingertip force sensors were mounted to measure the force distribution pattern of individual fingers during handle stabilization. The distinct behavior of the little finger was studied when the unsteady thumb platform was translated in the vertical direction towards the index and little finger end. In addition to this, the kind of task that lends support to the mechanical advantage hypothesis was investigated. Thus, the current research helps to understand why and in what situation the central nervous system prefers to employ the strategy of mechanical advantage principle while holding a handle