13th December 2023 marks P.W. Anderson’s 100th birth anniversary. Anderson (1923-2020) was one of the most successful theoretical physicists in his time. His insights, methods, model building, finding solutions and making predictions had far reaching implications in several branches in science. Based on my personal appreciation of Anderson's research from my PhD days, and later as a long time collaborator, I will describe what I believe to be a secret behind Anderson's remarkable success and present some examples. Briefly, Anderson, a theorist par excellence, was guided by nature, in the form of experimental results at each and every step.