Generally, homogeneous mixture combustion is preferred at high loads of conventional spark-ignition engines. But, in these engines, a homogeneous mixture at low loads can lead to high hydrocarbon (HC) emissions. Thereby, stratified mixture combustion with an overall lean mixture is preferred at low loads, which can significantly reduce HC emissions, but nitrogen oxide (NOx) and soot emissions will increase. Nowadays, gasoline direct injection (GDI) engines are becoming popular because of better thermal efficiency and low emissions at all loads. These engines work with a stratified mixture at low-load conditions and a homogeneous mixture at high-load conditions. But the problem with them is considerably high NOx and soot emissions during the low load conditions. Therefore, today, the concept of partial stratification is tried in these engines, which is a combination of the combustion of stratified and homogeneous mixtures, using both GDI and PFI (GDI-PFI) techniques. With the partial stratified mixture combustion, HC, NOx, and soot emissions are expected to reduce. The partially stratified mixture can also be formed by gasoline direct multiple injection (GDMI) mode. However, in GDMI mode higher wall wetting can be found than the GDI-PFI mode. This leads to higher HC emissions for the GDMI mode than the GDI-PFI mode. Also, the use of laser ignition instead of spark ignition has the potential to reduce NOx and HC emissions. Therefore, this paper deals with the study on the effect of spark and laser ignitions on the combustion, performance, and emission characteristics of a GDI-PFI engine operating with a partially stratified mixture using a CFD analysis. For the analysis, three overall equivalence ratios (OERs) of 0.9, 0.7, and 0.5 are considered. The effects of spark and laser ignitions are studied on the TKE formation at the ignition spot, IMEP, and emissions. The study is performed by maintaining a constant CA50 at 21 CAD after TDC, which is done by adjusting the SOS. Results showed that the combustion with the laser ignition is faster by about 52.6% than that of the spark ignition. The laser ignition with the split fraction of 0.6 and the OER of 0.7 reduced the HC and soot emissions by about 6.1% and 1.19 times that of the spark ignition mode. The IMEP for the laser ignition is improved by about 9.4% than the spark ignition. However, the NOx emissions increased by about 3% with the laser ignition.