Solar energy is one of the emerging technologies, and the use of concentrating power technology is increasing in solar power plants. Solar parabolic trough collector is the most established technology among other concentrating solar energy technologies, and its performance is influenced by slope error on mirror facets. The structural stability of collectors under wind and design loads determines the ability to accurately concentrate the rays at the absorber tube, which affects the overall optical and thermal efficiencies. The present study describes a methodology for the indigenous parabolic collector of 5.77 m aperture and 4 m width developed at IIT Madras to understand the pressure distribution over the surface and its subsequent effect over the slope error. Slope error values increase by 10.7% and 11.2% in elastic and cantilever cases compared to the rigid case under gravity load alone. It is observed that for a change in velocity from 5 m/s to 25 m/s, slope errors increase from 1.21 mrad to 3.11 mrad at the surface of the reflector exceeding the shape quality of the mirror panels. Higher yaw angles and pitch angles of 60° and 120° are observed to be decisive in the design of collectors. Roof-mounted collectors experience a 40% higher drag force than ground-mounted collectors at a 0° pitch angle. For the Aluminium trough, the slope error at the surface of the reflector is higher by 4.62% than glass. The study will be helpful for engineers and scientists in the design and optimization of the parabolic trough collectors.