"Design and development of endovascular coil embolization in intracranial aneurysms"
Date16th Oct 2023
Time03:00 PM
Venue https://meet.google.com/aha-prdv-yob
PAST EVENT
Details
Cerebral aneurysms are bulges of an artery, which could be life-threatening, when ruptured. Depending on its size, shape, location and rupture potential, they need to be managed. Typical clinical management approaches include clipping, endovascular coiling, coiling with a flow diverter etc. When coiled, reduced hemodynamic activity enables the coil to get thrombosed and achieve flow stasis. However, some coils delivered into the aneurysm tend to prolapse into the parent vessel and cause stroke due to obstruction and embolization. The recurrence of an aneurysm after endovascular coiling is of concern in the treatment of some aneurysms. Present study proposes design and development of various endovascular coiling related options that would result in successful outcomes. To this end, patient-specific CFD simulations are performed to study coil filled aneurysms using porous medium based formulation. It is proposed to investigate the influence of various hemodynamic parameters to design and develop optimal coil packing density and fill volume under various conditions. It is also proposed to study the influence of cell level activity leading to thrombus formation and attendant endothelialization.
Speakers
Mr. NISANTH KUMAR P (AM20D601)
Department of Applied Mechanics & Biomedical Engineering