Distilleries are one of the highly polluting industries, which have been classified under the red category industries in terms of environmental pollution perspectives. The distillery effluent contains very huge quantities of suspended and dissolved constituents including recalcitrant compounds such as melanoidin and phenolics, which makes the effluent treatment costly and energy intensive. Distillery industries adopt anaerobic digestion (AD) for the degradation of biodegradable portion of COD and generate energy in the form of methane. However, AD removes the pollutants only to a lesser extent, and a majority of recalcitrant compounds were found to be present in the anaerobically digested distillery wastewater (ADWW). This research work is aimed at developing a sequential coagulation-flocculation process (C-F) followed by algal photo-bioreactor for treating the effluent from AD. In the first seminar, the characterization of distillery wastewater, major parameters affecting the C-F process and its optimization for effective treatment of ADWW are presented in detail. In this seminar, the selection and enrichment of algal species, its growth studies, and the optimization of several key parameters for scaling-up of algal photobioreactors including photoperiod, light intensity, aeration conditions, feed dilution ratio, mode of operation, and hydraulic retention time (HRT) on the treatment of C-F treated ADWW will be discussed. Moreover, the C-F sludge and algal biomass generated during the sequential treatment processes were characterized, and the expected potential of energy generation will also be highlighted in the seminar. Finally, the toxicity of the ADWW and the toxicity of effluents at various stages of the sequential treatment will be discussed.