Current research on technostressors mostly focuses on their negative impact in the workplace, despite growing evidence about their positive influence on employee attitudes and performance (Tarafdar et al., 2019). In order to address this negative bias, first, the study uses the Job Demands-Resources theory to challenge the predominant stressor perspective of technostressors, and instead examines them as a nested sub-system of job demands differentially impacting organization-relevant outcomes of burnout and work engagement. Second, the study investigates psychological need satisfaction as a mediating variable in order to address questions of how technostressors impact outcomes (Day et al., 2015). Third, the study evaluates the extent to which technostress inhibitors, mindfulness and LMX quality moderate the effects of the mediated relationship of technostressors to outcomes. The population for the study comprises professionals from the Indian Information Technology (IT)/ Information Technology Enabled Services (ITES) sector. Data was collected using a self-administered online survey. Following a preliminary data screening to ensure inclusion criteria were met and unengaged responses removed, reliability and validity checks were performed. Subsequently, model fit analyses for the measurement and structural models were conducted. The results of data analysis fully support the nested sub-system model of technostressors and mediation by psychological need satisfaction. Partial support was obtained with regard to moderation by the three types of resources. Theoretical and practical implications are further discussed.