PROXiMATE: Protein-protein complex mutation thermodynamics database. The complex shown here is 1DVF.

PROXiMATE: PROtein-protein compleX MutAtion ThErmodynamics Database

Indian Institute of Technology Madras

ADVANCED SEARCH

Type any term here for quick search
Type the Entry ID (any number from 1 to 6296)

Use the Build Query table to input your search query, and choose which columns to display using the Display Columns table.
A short description of each search term can be seen by hovering the mouse over it. For more information, see the Tutorial.
BUILD SEARCH QUERY
Protein Complex: Protein 1 Protein 2
PDB ID
Residue mutation from to
Functional Class
Experimental technique used
Secondary Structure   Interface Residue? YesNoBoth
Relative accessibility to
Wild-type KD (M) from to
Mutant KD (M) from to
Wild-type ΔG (kcal/mol) from to
ΔΔG (kcal/mol) from to
Author
Reference Year from to
DISPLAY COLUMNS
PDB Interacting Chains Mutation(s) Functional Class
Protein 1 Protein 2 Secondary Structure Relative Accessibility
Experimental Conditions
Technique used Temperature Ionic Conditions pH
Data Values
Wild-type KD (M) Mutant KD (M) Wild-type ΔG (kcal/mol) ΔΔG (kcal/mol)
Wild-type kon (1/Ms) Mutant kon (1/Ms) Wild-type koff (1/s) Mutant koff (1/s)
Wild-type ΔH (kcal/mol) Mutant ΔH (kcal/mol) Wild-type ΔS (cal/mol K) Mutant ΔS (cal/mol K)
References
Pubmed/Reference Authors Title Journal
Volume Pages Year Database Source
Results per page
Protein Bioinformatics Lab, Department of Biotechnology, Indian Institute of Technology Madras, Chennai, India. Last updated 11 February 2021. FAQs | Cite Us | Usage Notice | Contact Us | Important Links