Minimum and Maximum values
ASA | T | pH | ΔGH2O | ΔΔGH2O | ΔΔG | Tm | ΔTm | ΔH | ΔCp | |
---|---|---|---|---|---|---|---|---|---|---|
min | 0 | -16 | 0.34 | -20.9 | -12.23 | -30.71 | -52.6 | -60.79 | -0.6 | -4.8 |
max | 249.1 | 133.6 | 13 | 85 | 13.7 | 23.7 | 389.5 | 72 | 1260 | 360 |
Average Stabilizing and Destabilizing values
ΔTm | ΔΔG | ΔH | ΔCp | ΔΔGH2O | ΔGH2O | Tm | |
---|---|---|---|---|---|---|---|
Avg Destabilizing | -7.25 | -2.76 | -0.6 | -1.64 | -2 | -3.66 | -18.61 |
Avg Stabilizing | 4.58 | 1.83 | 121.3 | 4.8 | 1.33 | 7 | 81.59 |
Mutation frequency count for whole dataset point mutations
A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A | 0 | 60 | 15 | 74 | 37 | 216 | 13 | 39 | 63 | 192 | 37 | 21 | 105 | 35 | 28 | 103 | 57 | 183 | 10 | 8 |
C | 226 | 0 | 2 | 4 | 4 | 5 | 0 | 4 | 0 | 27 | 2 | 0 | 1 | 0 | 0 | 165 | 114 | 25 | 5 | 2 |
D | 272 | 33 | 0 | 79 | 34 | 69 | 77 | 13 | 200 | 23 | 4 | 213 | 14 | 45 | 16 | 26 | 22 | 11 | 8 | 7 |
E | 369 | 10 | 43 | 0 | 39 | 64 | 14 | 7 | 426 | 55 | 16 | 13 | 8 | 326 | 151 | 36 | 12 | 70 | 18 | 39 |
F | 255 | 7 | 5 | 9 | 0 | 5 | 7 | 39 | 11 | 139 | 20 | 27 | 4 | 2 | 2 | 43 | 10 | 33 | 96 | 109 |
G | 403 | 18 | 38 | 41 | 16 | 0 | 20 | 0 | 9 | 9 | 0 | 5 | 19 | 28 | 25 | 64 | 2 | 62 | 6 | 2 |
H | 207 | 10 | 22 | 25 | 17 | 47 | 0 | 0 | 7 | 58 | 0 | 91 | 24 | 53 | 29 | 6 | 9 | 10 | 7 | 110 |
I | 363 | 29 | 18 | 30 | 95 | 46 | 12 | 0 | 13 | 351 | 75 | 3 | 7 | 2 | 9 | 27 | 66 | 540 | 21 | 14 |
K | 287 | 20 | 14 | 325 | 62 | 92 | 44 | 36 | 0 | 12 | 61 | 32 | 27 | 241 | 100 | 13 | 21 | 47 | 28 | 21 |
L | 523 | 68 | 13 | 70 | 90 | 37 | 6 | 111 | 14 | 0 | 75 | 9 | 33 | 16 | 26 | 17 | 19 | 145 | 23 | 14 |
M | 88 | 3 | 6 | 8 | 20 | 20 | 0 | 49 | 20 | 151 | 0 | 1 | 2 | 0 | 24 | 0 | 12 | 67 | 2 | 2 |
N | 208 | 17 | 152 | 31 | 5 | 48 | 82 | 65 | 46 | 7 | 13 | 0 | 2 | 6 | 21 | 50 | 14 | 9 | 3 | 15 |
p | 215 | 9 | 6 | 5 | 6 | 75 | 3 | 2 | 6 | 18 | 0 | 4 | 0 | 5 | 8 | 83 | 17 | 11 | 4 | 2 |
Q | 101 | 12 | 12 | 39 | 7 | 69 | 6 | 15 | 41 | 26 | 3 | 14 | 9 | 0 | 23 | 5 | 9 | 3 | 2 | 22 |
R | 224 | 34 | 5 | 113 | 7 | 53 | 102 | 12 | 47 | 18 | 26 | 5 | 5 | 67 | 0 | 31 | 6 | 18 | 12 | 4 |
S | 317 | 81 | 79 | 22 | 21 | 79 | 25 | 11 | 50 | 18 | 2 | 20 | 64 | 4 | 42 | 0 | 59 | 19 | 5 | 6 |
T | 251 | 57 | 30 | 104 | 28 | 44 | 24 | 167 | 19 | 40 | 13 | 37 | 37 | 33 | 42 | 152 | 0 | 163 | 5 | 36 |
V | 667 | 73 | 29 | 67 | 111 | 119 | 12 | 392 | 63 | 366 | 103 | 46 | 12 | 48 | 26 | 65 | 156 | 0 | 25 | 51 |
W | 77 | 5 | 4 | 4 | 220 | 0 | 21 | 0 | 0 | 31 | 3 | 1 | 0 | 7 | 9 | 3 | 5 | 2 | 0 | 108 |
Y | 150 | 20 | 25 | 270 | 258 | 41 | 10 | 3 | 4 | 48 | 4 | 7 | 17 | 8 | 2 | 13 | 5 | 12 | 136 | 0 |
Mutation frequency for the whole dataset point mutations %
A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A | 0 | 0.29 | 0.07 | 0.36 | 0.18 | 1.04 | 0.06 | 0.19 | 0.3 | 0.92 | 0.18 | 0.1 | 0.5 | 0.17 | 0.13 | 0.49 | 0.27 | 0.88 | 0.05 | 0.04 |
C | 1.09 | 0 | 0.01 | 0.02 | 0.02 | 0.02 | 0 | 0.02 | 0 | 0.13 | 0.01 | 0 | 0 | 0 | 0 | 0.79 | 0.55 | 0.12 | 0.02 | 0.01 |
D | 1.31 | 0.16 | 0 | 0.38 | 0.16 | 0.33 | 0.37 | 0.06 | 0.96 | 0.11 | 0.02 | 1.02 | 0.07 | 0.22 | 0.08 | 0.12 | 0.11 | 0.05 | 0.04 | 0.03 |
E | 1.77 | 0.05 | 0.21 | 0 | 0.19 | 0.31 | 0.07 | 0.03 | 2.05 | 0.26 | 0.08 | 0.06 | 0.04 | 1.57 | 0.73 | 0.17 | 0.06 | 0.34 | 0.09 | 0.19 |
F | 1.22 | 0.03 | 0.02 | 0.04 | 0 | 0.02 | 0.03 | 0.19 | 0.05 | 0.67 | 0.1 | 0.13 | 0.02 | 0.01 | 0.01 | 0.21 | 0.05 | 0.16 | 0.46 | 0.52 |
G | 1.94 | 0.09 | 0.18 | 0.2 | 0.08 | 0 | 0.1 | 0 | 0.04 | 0.04 | 0 | 0.02 | 0.09 | 0.13 | 0.12 | 0.31 | 0.01 | 0.3 | 0.03 | 0.01 |
H | 0.99 | 0.05 | 0.11 | 0.12 | 0.08 | 0.23 | 0 | 0 | 0.03 | 0.28 | 0 | 0.44 | 0.12 | 0.25 | 0.14 | 0.03 | 0.04 | 0.05 | 0.03 | 0.53 |
I | 1.74 | 0.14 | 0.09 | 0.14 | 0.46 | 0.22 | 0.06 | 0 | 0.06 | 1.69 | 0.36 | 0.01 | 0.03 | 0.01 | 0.04 | 0.13 | 0.32 | 2.59 | 0.1 | 0.07 |
K | 1.38 | 0.1 | 0.07 | 1.56 | 0.3 | 0.44 | 0.21 | 0.17 | 0 | 0.06 | 0.29 | 0.15 | 0.13 | 1.16 | 0.48 | 0.06 | 0.1 | 0.23 | 0.13 | 0.1 |
L | 2.51 | 0.33 | 0.06 | 0.34 | 0.43 | 0.18 | 0.03 | 0.53 | 0.07 | 0 | 0.36 | 0.04 | 0.16 | 0.08 | 0.12 | 0.08 | 0.09 | 0.7 | 0.11 | 0.07 |
M | 0.42 | 0.01 | 0.03 | 0.04 | 0.1 | 0.1 | 0 | 0.24 | 0.1 | 0.73 | 0 | 0 | 0.01 | 0 | 0.12 | 0 | 0.06 | 0.32 | 0.01 | 0.01 |
N | 1 | 0.08 | 0.73 | 0.15 | 0.02 | 0.23 | 0.39 | 0.31 | 0.22 | 0.03 | 0.06 | 0 | 0.01 | 0.03 | 0.1 | 0.24 | 0.07 | 0.04 | 0.01 | 0.07 |
p | 1.03 | 0.04 | 0.03 | 0.02 | 0.03 | 0.36 | 0.01 | 0.01 | 0.03 | 0.09 | 0 | 0.02 | 0 | 0.02 | 0.04 | 0.4 | 0.08 | 0.05 | 0.02 | 0.01 |
Q | 0.49 | 0.06 | 0.06 | 0.19 | 0.03 | 0.33 | 0.03 | 0.07 | 0.2 | 0.12 | 0.01 | 0.07 | 0.04 | 0 | 0.11 | 0.02 | 0.04 | 0.01 | 0.01 | 0.11 |
R | 1.08 | 0.16 | 0.02 | 0.54 | 0.03 | 0.25 | 0.49 | 0.06 | 0.23 | 0.09 | 0.12 | 0.02 | 0.02 | 0.32 | 0 | 0.15 | 0.03 | 0.09 | 0.06 | 0.02 |
S | 1.52 | 0.39 | 0.38 | 0.11 | 0.1 | 0.38 | 0.12 | 0.05 | 0.24 | 0.09 | 0.01 | 0.1 | 0.31 | 0.02 | 0.2 | 0 | 0.28 | 0.09 | 0.02 | 0.03 |
T | 1.21 | 0.27 | 0.14 | 0.5 | 0.13 | 0.21 | 0.12 | 0.8 | 0.09 | 0.19 | 0.06 | 0.18 | 0.18 | 0.16 | 0.2 | 0.73 | 0 | 0.78 | 0.02 | 0.17 |
V | 3.2 | 0.35 | 0.14 | 0.32 | 0.53 | 0.57 | 0.06 | 1.88 | 0.3 | 1.76 | 0.49 | 0.22 | 0.06 | 0.23 | 0.12 | 0.31 | 0.75 | 0 | 0.12 | 0.24 |
W | 0.37 | 0.02 | 0.02 | 0.02 | 1.06 | 0 | 0.1 | 0 | 0 | 0.15 | 0.01 | 0 | 0 | 0.03 | 0.04 | 0.01 | 0.02 | 0.01 | 0 | 0.52 |
Y | 0.72 | 0.1 | 0.12 | 1.3 | 1.24 | 0.2 | 0.05 | 0.01 | 0.02 | 0.23 | 0.02 | 0.03 | 0.08 | 0.04 | 0.01 | 0.06 | 0.02 | 0.06 | 0.65 | 0 |