Nanoscale materials have attracted great interests in recent years. Low dimensional systems such as 2D materials, nanoparticles, nanorods, nanowalls or networks are an important category of nanostructured materials with great potential as important components for nanoscale devices with various interesting functions. Thus, in the past decade, many techniques have been developed for the synthesis of such nanostructured materials. In addition, researchers have put in great effort in the studies of hybrid nanomaterials. With these efforts, a wide variety of nanostructured materials have been investigated. After the synthesis of the nanomaterials, it is desirable to be able to further modify the properties of the nanomaterials to improve the functionality of these nanomaterials. If we can create micropatterns on these as-grown nanomaterials, it will be able to further expand their potential applications. In recent years, efforts involve the alteration of physical and/or chemical properties of nanomaterials via the use of a focused laser beam have generated a lot of interests. In this presentation, we will present our efforts in the studies of hybrid nanomaterials with the emphasis on how the focused laser beam can be utilized. We shall also highlight a few carbon-based hybrid nanomaterials and also 2D TMDCs investigated via this method.