| S.No. | Title | Role | Funding Agencies | Duration | Amount (Rs. in lakhs) |
|---|---|---|---|---|---|
| 1. | Controlling Papaya Ring Spot Virus transmission by interfering Protein-Protein Interactions through biogenic nano-porous silica formulations: Systematic Modeling and Molecular Dynamics Investigations. NNP-TNAU, Coimbatore. | PI | Department of Biotechnology, Govt.of India. | 2024-2027 | 18.21 |
| 2. | Accelerating identification of RNA-targeted therapeutics to mitigate breast cancer through development of computational methods. | PI | Indian Council of Medical Research, Govt. of India. | 2025-2028 | 65.89 |
| 3. | Identification of Potent Drug for Life-Threatening Diseases. NNP-Alagappa University, Karaikudi. | PI | Department of Biotechnology, Govt. of India. | 2023-2028 | 24.22 |
| 4. | Genome informatics networks to understand plant stress management. NNP-NCBS, Bengaluru.) | PI | Department of Biotechnology, Govt. of India. | 2023-2028 | 55.68 |
| 5. | Development of a comprehensive database for disease causing mutations and tool for predicting the binding affinity of protein carbohydrate complexes: influence of binding affinity on disease causing mutations | PI | Department of Biotechnology, Govt. of India. | 2024-2027 | 37.48 |
| 6. | Explore Viral Involvement in the Alzheimer’s Amyloid Beta Peptides Toxicity: Multiscale In-Silico Experimental Approach | PI | Science and Engineering Research Board (SERB), Govt. of India. | 2024-2026 | 29.80 |
| S.No. | Title | Role | Funding Agencies | Duration | Amount (Rs. in lakhs) |
|---|---|---|---|---|---|
| 1. | A Method to improve Modelling of Protein-protein Complexes using AlphaFold2 and Filtered Coevolutionary Signals. | PI | Department of Biotechnology, Govt. of India. | 2022-2024 | 14.98 |
| 2. | An Integrative Approach for Understanding the Structure, Function and Dynamics of HIV Protease: Applications to Design Novel Inhibitors | PI | Department of Science and Technology, Govt. of India. | 2021-2024 | 34.55 |
| 3. | Efficacy of HSP90 mitochondrial targeting of Withanolide A & Withaferin A in Hepatocellular carcinoma | PI | Science and Engineering Research Board (SERB), Govt. of India. | 2020-2024 | 18.2 |
| 4. | Integrated approach for understanding the binding affinity of protein-nucleic acid complexes: development of database, tools and applications to diseases | PI | Science and Engineering Research Board (SERB), Govt. of India. | 2020-2023 | 38.47 |
| 5. | Structure based drug design and mechanistic studies for COVID19 | PI | Science and Engineering Research Board (SERB), Govt. of India. | 2020-2023 | 18.2 |
| 6. | Adapting the standard SIR model for COVID-19 and effects of climate and lockdowns on infectious spread of SARS-CoV-2 | PI | Science and Engineering Research Board (SERB), Govt. of India. | 2020-2021 | 5.5 |
| 7. | Identification of therapeutic targets for Glioblastoma by Single-Cell RNA-Seq Analysis. | PI | Department of Health Research, Govt. of India. | 2020-2022 | 42 |
| 8. | Elucidation of mechanism of Drug resistance associated with Breast Cancer and Ovarian Cancer through network biology approach. | PI | Science and Engineering Research Board (SERB), Govt. of India. | 2019-2022 | 18 |
| 9. | Predictive modeling of nucleic acid recognition dynamics and structured complex formation by disordered proteins | PI | Council of Scientific and Industrial Research, Govt. of India. | 2019-2021 | 17 |
| 10. | Tackling COVID-19: Repurposing of therapeutic antibodies and development of a comprehensive antibody database | PI | Robert Bosch Centre for Data Science and Artificial Intelligence, IIT Madras | 2020-2021 | 11.42 |
| 11. | A computational pipeline for understanding disease-causing mutations in Genomes Algorithms for context analysis and Development of Prediction Tools: Development of computational tools for analysis and prediction of disease-causing mutations | PI | Department of Biotechnology, Govt. of India. | 2017-2020 | 38 |
| 12. | Structural and molecular approach of targeting Bcl-2 family anti-apoptotic proteins | PI | Department of Biotechnology, Govt. of India. | 2017-2020 | 41 |
| 13. | Mutational effects on binding affinity of protein-protein complexes: development of a database, tools and applications to diseases | PI | Science and Engineering Research Board (SERB), Govt. of India. | 2017-2020 | 27 |
| 14. | Prediction of disease-relevant mutations in transmembrane proteins | PI | Department of Science and Technology, India and Russian Science Foundation, Russia | 2016-2019 | 71 |
| 15. | Design of Sialic acid analog inhibitors to Hemagglutinins and Neuraminidases of Influenza virus by Molecular Modelling and Molecular Dynamics Simulation | Co-PI | Department of Biotechnology, Govt. of India. | 2016-2019 | 32 |
| 16. | Research grant under Institute Research and Development Award at mid-career level | PI | Indian Institute of Technology Madras | 2016-2019 | 30 |
| 17. | Development of three dimensional structural database for biologically and functionally important glycans and glycan-protein complexes through molecular dynamics simulation | Co-PI | Department of Biotechnology, Govt. of India. | 2016-2019 | 40 |
| 18. | Deep learning in life sciences | PI | Department of Science and Technology, India and Swedish (VR) Corporation | 2017-2019 | 29 |
| 19. | Targeted inhibition of Bcl-2 Anti-apoptotic protein using in silico and in vitro approaches | PI | IC&SR, Indian Institute of Technology Madras | 2017-2018 | 9.5 |
| 20. | Investigating protein aggregation using structural analysis, prediction methods and molecular dynamics study with applications to an eye disease, corneal dystrophy | PI | Department of Biotechnology, Govt. of India. | 2013-2017 | 37 |
| 21. | Dissecting important amino acid residues for folding and binding of proteins | PI | Department of Science and Technology, Govt. of India. | 2013-2016 | 24 |
| 22. | Development of tools for functional annotation of membrane proteins | PI | Indian Institute of Technology Madras | 2011-2014 | 5 |
| 23. | Development of database for functional residues in membrane proteins | PI | Computational Biology Research Center, Japan | 2008-2009 | 4 |
| 24. | Research on recognition mechanism for biomolecular complexes using grid computing | Co-PI | Japan Science and Technology, Japan and Department of Science and Technology, India | 2008-2011 | 75 |
| 25. | Development of database and algorithms for understanding and predicting functional residues in membrane proteins | PI | Computational Biology Research Center, Japan | 2007-2008 | 7 |
| 26. | Annotation of outer membrane proteins in genomic sequences and development of database for retrieving OMPs through query based system | PI | Computational Biology Research Center, Japan | 2005-2006 | 16 |
| 27. | Integration of bioinformatics tools and database for annotating outer membrane proteins in genomic sequences | PI | Okawa Science Foundation, Japan | 2005-2006 | 5 |
| 28. | Development of online tools for identifying outer membrane proteins in genomic sequences | PI | Computational Biology Research Center, Japan | 2005-2006 | 14 |
| 29. | Development of integrated biomolecular databases and analyzing systems | Co-PI | Ministry of Education, Culture, Sports and Technology, Japan | 2004-2005 | 29 |
| 30. | Inter-residue interactions in protein structures | Co-PI | The Daiwa Anglo-Japan Foundation, UK | 2004-2005 | 8 |